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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TKTL2 All Species: 0
Human Site: S292 Identified Species: 0
UniProt: Q9H0I9 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H0I9 NP_115512.3 626 67877 S292 N E N L I P K S P V E D S P Q
Chimpanzee Pan troglodytes Q5R1W6 623 67821 P288 K K K I L A T P P Q E D A P S
Rhesus Macaque Macaca mulatta XP_001095403 703 76522 P369 N E N P R P K P P V E D S P Q
Dog Lupus familis XP_538204 596 64805 E265 L E P K P P I E D S P P V N I
Cat Felis silvestris
Mouse Mus musculus Q9D4D4 627 68429 P293 N R N L T P K P P I E D S P R
Rat Rattus norvegicus P50137 623 67625 P288 K K K I L A T P P Q E D A P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508404 725 77819 L390 K K K I L A A L P E E D A P V
Chicken Gallus gallus XP_414333 627 68436 L288 K K K L S P A L P E E D A P V
Frog Xenopus laevis NP_001079885 625 67433 V291 N K K I C P L V P T A D A P K
Zebra Danio Brachydanio rerio NP_932336 625 67820 P291 N K P L Y P Q P P K E D A P P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623357 627 67899 P293 L G L H P Q K P L V D D V S V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P23254 680 73787 K303 H Y Q K T I L K P G V E A N N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 66.1 85.9 75.4 N.A. 80.5 66.1 N.A. 56.8 66.5 72 69.3 N.A. N.A. 60.1 N.A. N.A.
Protein Similarity: 100 79.5 86.7 83 N.A. 89.4 79.5 N.A. 69 80.5 84.8 83.3 N.A. N.A. 75.5 N.A. N.A.
P-Site Identity: 100 26.6 80 13.3 N.A. 66.6 26.6 N.A. 26.6 40 33.3 46.6 N.A. N.A. 20 N.A. N.A.
P-Site Similarity: 100 53.3 80 13.3 N.A. 80 53.3 N.A. 53.3 53.3 60 66.6 N.A. N.A. 26.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.4 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 43 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 25 17 0 0 0 9 0 59 0 0 % A
% Cys: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 9 0 9 84 0 0 0 % D
% Glu: 0 25 0 0 0 0 0 9 0 17 67 9 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 9 0 0 0 0 0 0 0 9 0 0 0 0 0 % G
% His: 9 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 34 9 9 9 0 0 9 0 0 0 0 9 % I
% Lys: 34 50 42 17 0 0 34 9 0 9 0 0 0 0 9 % K
% Leu: 17 0 9 34 25 0 17 17 9 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 42 0 25 0 0 0 0 0 0 0 0 0 0 17 9 % N
% Pro: 0 0 17 9 17 59 0 50 84 0 9 9 0 75 9 % P
% Gln: 0 0 9 0 0 9 9 0 0 17 0 0 0 0 17 % Q
% Arg: 0 9 0 0 9 0 0 0 0 0 0 0 0 0 9 % R
% Ser: 0 0 0 0 9 0 0 9 0 9 0 0 25 9 17 % S
% Thr: 0 0 0 0 17 0 17 0 0 9 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 9 0 25 9 0 17 0 25 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 0 9 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _